Respiratory tract infections (RTIs) are very common in all age groups. As a large number of pathogens cause respiratory infection including both viruses and bacteria, knowledge of the etiology of an RTI is essential to facilitate the appropriate treatment of patients and reduces the inappropriate use of drugs.
The diagnosis methods of identifying pathogens in respiratory secretions specimens have been developed over many years. Initially, cell cultures, immunofluorescence assays, and rapid antigen direct tests were all used in identifying RTI pathogens. However, none of those methods are ideal for clinical use as they are either expensive, lack of sensitivity and specificity, or have a long turnaround time.
In recent years, those problems have been overcome with advanced molecular diagnostic methods in clinical use. FDA 510(k) Cleared Respiratory Pathogen Panel (RPP) is capable of the simultaneous detection and identification of nucleic acids from multiple viruses and bacteria extracted from nasopharyngeal swab (NPS) samples obtained from individuals with signs and/or symptoms of respiratory tract infection. This fully automated system can process up to 94 patient samples simultaneously. Thereby, RPP can provide appropriate results to physicians within a short turnaround time (24-48 hours after sample receiving, or the same day if it's STAT case. ) to aid RTI pathogen diagnosis.
17 pathogens identified:
Subtype H1 2009pdm
▪Respiratory Syncytial Virus A and B
▪Human Metapneumovirus A and B
▪Coronavirus (229E, OC43, HKU1, and NL63)
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